Remove the lead and mercury from your body through chelation

IAS News 19 June 2017 | 0 Comments

Heavy metals decrease the number of stem cells and when removed by chelation the number of stem cells rise. By removing the lead, mercury, cadmium out of your body it will ensure stem cells to work to their full potential. A study by Nina Mikirova et, al, investigates into the efficacy of oral DMSA and intravenous EDTA in chelation of toxic metals and improvement of the number of stem/ progenitor cells in circulation.

Toxic metals such as mercury, lead, aluminium and arsenic cause a substantial amount of fear for our health. Damage by these metals include, inducing behavioural dysfunction, damage central and peripheral nervous systems, compromise kidney and liver function, and harm haemopoietic cardiovascular systems. The main devices in causing metal toxicity include alteration of cellular pro-oxidant anti-oxidant homeostasis and binding of metal ions to key cellular proteins.

The Study

Information was gained from over four hundred participants who received chelation therapy for long-term non-occupational toxic metal exposure. The breakdown of specific treatments is as follows: oral DMSA (500 mg) for 160 subjects; intravenous low dose Na-EDTA (1 g) for 50 subjects; and intravenous high dose EDTA (Ca-EDTA or Na-EDTA) (3 g) for 200 subjects. Prior to treatment, each subject was screened for adequate kidney functioning by assaying fasting serum creatinine (levels below 1.7 mg/dL were considered acceptable). Urine samples were collected pre and post treatment for toxic metal excretion analysis.

Based on results from the study, the following conclusions were drawn:

• The toxic metals lead and mercury inhibit the mesenchymal stem cell metabolism and proliferation and adult differentiated cell metabolism in vitro. In fact, MSCs are more sensitive to these metals than differentiated cells such as lung fibroblasts and HUVEC.

• The chelating agent DMSA increases circulating CD34- positive cell numbers in vivo.

• In comparison to EDTA, DMSA chelation by eqiumolar concentration is better at extracting lead and arsenic, comparable in extracting aluminum, and less efficient in extracting cadmium.

• In the extraction of essential minerals during chelation, DMSA is highly ‘efficient’ in removing copper, and is in general more likely than EDTA to cause extraction of essential minerals (with the exception of manganese and zinc, which are extracted more in EDTA chelation).

• DMSA shows some ability to extract mercury, but this requires several treatments.

• In vitro lead uptake assay showed that while both antidotes reduce cellular lead uptake in a concentration dependent fashion, DMSA appears to have the larger effect.

 

To summarise researches believe that chelation therapy displays promise in repairing metal toxicity damage and restoring circulating stem cell populations. There is hope that this study will embark on a larger scale to gain more data on changes in white cell and progenitor cell numbers before and after chelation therapy.

For the full research study and more information, please follow the links below:

 

1.) http://www.transbiomedicine.com/translational-biomedicine/efficacy-of-oral-dmsa-and-intravenous-edta-in-chelation-of-toxic-metals-and-improvement-of-the-number-of-stem-progenitor-cells-in-circulation.php?aid=2543

 

2.) http://www.transbiomedicine.com TRANSLATIONAL BIOMEDICINE, 2011, Vol. 2 No. 2:2 doi: 10:3823/424

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