Telomeres and age related disease

IAS News 3 April 2013 | 0 Comments

The link between developing age related diseases and biological aging has been found by scientists led by Leicester University. Involving 14 research centers across a total of 8 countries the study looked into telomeres – which IAS is sure everyone has now heard about (if not read more about them here!) To keep it short, they decrease in length each time a cell divides, therefore getting shorter as an individual ages. Different people have different length telomeres to begin with, and even then each takes varying lengths of time to shorten, which is why it is a great measure of biological aging.
Although heart disease and cancers are more common as we age, it doesn’t mean that everyone will suffer from them – indeed some get them much earlier than usually expected. This has been linked to the possibility that some people simply age quick biologically.
48,000 individuals were looked into, and 7 genetic variants were linked with telomere length. The question was asked if these variants also changed an individuals chance of suffering from various diseases. By connecting the DNA with disease, cuts out the usual questions of whether the affect happened due to environment, or lifestyle as neither of these affect DNA.
Colorectal cancer, among other cancers, multiple sclerosis and celiac disease were all found to have links with the variants – as well as a strong link to coronary artery disease. This strong link between length of telomeres may go part of the way to explaining why some people develop diseases that are more commonly associated with aging in earlier life. Other studies have previously shown length of telomeres to be related to the risk of developing the common cold and dementia. Studies have also shown the link between exercise and length of telomeres.
IAS sells TA65 in both 30 and 90 capsules, which can increase the average length of the telomeres.

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